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Year : 2020  |  Volume : 40  |  Issue : 3  |  Page : 127-130

Pretibial myxedema: Paradoxical manifestation of thyroid dermopathy after I-131 ablation therapy

1 Department of Medicine, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan
2 Department of 2Dermatology, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan

Correspondence Address:
Dr. Chih-Tsung Hung
Department of Dermatology, Tri-Service General Hospital, No. 325, Sec. 2, Chenggong Rd., Neihu District, Taipei City 114
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmedsci.jmedsci_89_19

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Pretibial myxedema (PM) is an unusual extrathyroidal manifestation of Graves' disease (GD), which affects approximately 1%–5% of the patients. In addition, PM usually occurs in the hyperthyroid state of GD, and the high level of thyroid autoantibodies is considered to be the cause of PM. Here, we present a rare case of a patient who developed PM after undergoing I-131 ablation therapy, with normal levels of thyroid autoantibodies. Our report aims to document the features of PM in a male adult with hypothyroidism and to provide a potential mechanism of the onset of PM.

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