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Meigs syndrome caused by fibrothecoma of the ovary

1 Department of Obstetrics and Gynecology, Tri-Service General Hospital, Taipei, Taiwan
2 Department of Pathology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

Correspondence Address:
Mu-Hsien Yu,
11490, No. 325, Sec. 2, Cheng-Gong Road, Neihu District, Taipei
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/jmedsci.jmedsci_82_22

Huge or enlarged solid ovarian tumor, elevated serum CA-125 levels, massive ascites, and even pleural effusions are common features of ovarian cancer which have the worst outcome of gynecological malignancy. Here, we report a 53-year-old woman with fibrothecoma-associated Meigs syndrome mimicking ovarian malignancy, whose symptoms resolved gradually, and subsequently, serum CA-125 level declined to normal range after surgical intervention. The pathological diagnosis revealed fibrothecoma of the ovary compatible with Meigs syndrome containing the triad of benign ovarian tumor, ascites, and pleural effusion. Therefore, Meigs syndrome should be considered one of the clinical differential diagnoses for a large ovarian tumor with ascites, pleural effusion, and elevated CA-125.


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